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In order to investigate the pharmacological action of combined preparation of crude drugs, "Oyo-Tang" were studied. "Oyo-Tang" consist of Glycyrrhizae Radix, Ephedrae Herba, Armenicae Semen, Platycodi Radix and Nepetae Herba. They have widely been prescribed in Oriental Medicine for controlling of cough, asthma, nasal obstraction, pharygeal pain and hoarseness. Experimental studies were implemented on analgesic, sedative, anticonvulsive and ileum relaxing actions. The results of the studies were as follows; Significant anticonvulsive action was recognized by fraction IIII. Sedative and analgesic actions were noted by fraction I and III. Relaxing action was shown on the extracted ileum in mice, antagonistic actions were seen on BaCl₂^- induced contraction of the ileum of mice and Histamine-induced contraction of the ileum of guinea-pigs that the relaxing effect of the intestinal smooth muscle was recognized.
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